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Search Results for " dry eye disease "

6

Compounds

Cat No. Product Name Synonyms Targets
T3977 Lifitegrast SHP-606,SAR 1118 Integrin
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
T7423 Diquafosol tetrasodium INS365 P2Y Receptor
Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film stability and visual function, as a topical treatment of dr...
T28496 R-932348 choline R-932348,R 348,R 932348,R932348,R-348,R348
R-932348 choline, a dual JAK/SYK inhibitor, is used potentially for treatment of dry eye disease.
T39293 Tivanisiran SYL1001,Tivanisiran
Tivanisiran (SYL1001) is a siRNA developed specifically to inhibit the expression of transient receptor potential vanilloid 1 (TRPV1) to explore its implications in dry eye disease research.
T70346 TOP1362
TOP1362 is a Narrow Spectrum Kinase Inhibitors Demonstrate Promise for the Treatment of Dry Eye Disease and Other Ocular Inflammatory Disorders. TOP1362 strongly inhibited the kinase targets p38α, Syk, Src, and Lck, bloc...
T79235 JAK-IN-30 JAK
JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50) values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, an...
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